Table 1.

Baseline demographic and clinical features of patients who have type 1 diabetes with diabetic nephropathy and residual albuminuria on maximal ACEI treatment a

CharacteristicsAmlodipine(n = 14)Candesartan(n = 12)P Value
Male/female9/56/60.77
Mean age, yr (range)47 (33–61)47 (30–70)0.96
Mean duration of diabetes, yr (range)30 (14–46)31 (20–61)0.77
Geometric mean (interquartile range) ACR, mg/mmol25.7 (13–39.1)32.3 (12.2–89.8)0.44
MAP, mmHg103 ± 996 ± 130.10
Serum potassium, mmol/L4.5 ± 0.44.6 ± 0.40.33
GFR, ml/min90.1 ± 41.494.1 ± 23.90.76
HbA1c, %8.9 ± 1.59.7 ± 1.70.3
  • a Data are mean (SD) unless otherwise stated. ACEI, angiotensin-converting enzyme inhibitor; ACR, albumin creatinine ratio; MAP, mean arterial pressure; HbA1c, hemoglobin A1c.