Table 1.

Pretest probability of coronary disease

PPVNPV
10%21%95%
20%37%90%
30%50%84%
40%61%80%
50%70%70%
60%80%61%
70%84%50%
80%90%37%
  • In this table, noninvasive cardiac stress tests are assumed to have a sensitivity and specificity of 70% when applied to renal transplant candidates. The positive and negative predictive value (PPV and NPV) of the test result are presented based on the patient’s pretest probability of disease. Accordingly, the ability to satisfactorily exclude significant coronary disease (NPV > 75%) will only occur if the pretest disease probability is 40% or less.