Clinical and laboratory data of healthy subjects and patients with kidney diseasesa
| Healthy Subjects(n = 76) | Renal Patients(n = 227) | |
|---|---|---|
| Gender (male/female [%]) | 51/25 (67/33) | 154/73 (68/32) |
| Age (yr) | 44.3 ± 13.0 | 45.7 ± 12.6 |
| Body mass index (kg/m2) | 24.9 ± 2.9 | 25.2 ± 3.8 |
| Serum creatinine (mg/dl) | 0.92 (0.87 to 1.00) | 1.61 (1.21 to 2.37)b |
| GFR (ml/min per 1.73 m2) | — | 63 (38 to 96) |
| Proteinuria (g/24 h per 1.73 m2) | — | 0.52 (0.18 to 1.42) |
| Intact parathyroid hormone (pmol/L) | 4.1 (3.0 to 5.0) | 6.0 (3.7 to 13.0)b |
| High-sensitivity C-reactive protein (mg/L) | 0.91 (0.22 to 1.84) | 1.50 (0.70 to 3.90)b |
| Systolic BP (mmHg) | 123 ± 10 | 137 ± 21b |
| Diastolic BP (mmHg) | 75 ± 7 | 87 ± 14b |
| Pulse pressure (mmHg) | 48 ± 7 | 51 ± 15 |
| Insulin (mU/L) | 6.5 ± 2.3 | 13.9 ± 9.6b |
| Glucose (mg/dl) | 86 ± 7 | 98 ± 17b |
| HOMA-IR index | 1.39 ± 0.51 | 3.59 ± 3.55b |
| Adiponectin (μg/ml) | 6.6 ± 2.8 | 6.1 ± 4.2 |
| Total cholesterol (mg/dl) | 191 ± 33 | 215 ± 45c |
| LDL cholesterol (mg/dl) | 127 ± 26 | 136 ± 40 |
| Triglycerides (mg/dl) | 94 (74 to 124) | 144 (101 to 223)b |