Table 1.

Clinical and laboratory data of healthy subjects and patients with kidney diseasesa

Healthy Subjects(n = 76)Renal Patients(n = 227)
Gender (male/female [%])51/25 (67/33)154/73 (68/32)
Age (yr)44.3 ± 13.045.7 ± 12.6
Body mass index (kg/m2)24.9 ± 2.9 25.2 ± 3.8 
Serum creatinine (mg/dl)0.92 (0.87 to 1.00)1.61 (1.21 to 2.37)b
GFR (ml/min per 1.73 m2)63 (38 to 96)
Proteinuria (g/24 h per 1.73 m2)0.52 (0.18 to 1.42)
Intact parathyroid hormone (pmol/L)4.1 (3.0 to 5.0)6.0 (3.7 to 13.0)b
High-sensitivity C-reactive protein (mg/L)0.91 (0.22 to 1.84)1.50 (0.70 to 3.90)b
Systolic BP (mmHg)123 ± 10 137 ± 21b
Diastolic BP (mmHg)75 ± 787 ± 14b
Pulse pressure (mmHg)48 ± 751 ± 15
Insulin (mU/L)6.5 ± 2.313.9 ± 9.6b
Glucose (mg/dl)86 ± 798 ± 17b
HOMA-IR index1.39 ± 0.513.59 ± 3.55b
Adiponectin (μg/ml)6.6 ± 2.86.1 ± 4.2
Total cholesterol (mg/dl)191 ± 33215 ± 45c
LDL cholesterol (mg/dl)127 ± 26136 ± 40
Triglycerides (mg/dl)94 (74 to 124)144 (101 to 223)b
  • a HOMA-IR, Homeostasis Model Assessment of Insulin Resistance.

  • b P < 0.01, healthy subjects versus renal patients.

  • c P < 0.05, healthy subjects versus renal patients.