Table 1.

Criteria for defining LVH in the various studiesa

CHS and ARICFHS and Offspring
Voltage criteriaR-wave amplitude >26 mm in V5 or V6R-wave amplitude ≥25 mm in any deflection in precordial leads
R-wave amplitude >20 mm in any of leads I, II, III, aVFR-wave amplitude ≥20 mm in standard leads
R amplitude >12 in aVLR-wave amplitude ≥11 mm in augmented unipolar leads
R-wave amplitude >15 but ≤20 mm in lead I
R-wave amplitude in V5 or V6 plus S amplitude in V1 >35 mmR-wave amplitude in V5 or V6 plus S amplitude in V1 or V2 ≥35 mm
S-T segment characteristicsS-T depressionMinnesota Codes:anterolateral = 4–1–2, 4–2, 4–3posterior = 4–2, 4–3, 4–12anterior = 4–2, 4–3, 4–4–1, 4–1–2“Depressed S-T segments”
T wave characteristicsFlattened to inverted T wavesMinnesota Codes:anterolateral = 5–1, 5–2, 5–3posterior = 5–2, 5–3anterior = 5–1, 5–2, 5–3“Flattened to inverted T waves”
  • a LVH, left ventricular hypertrophy; CHS, Cardiovascular Health Study; ARIC, Atherosclerosis Risk in Communities Study; FHS, Framingham Heart Study; Offspring, Framingham Offspring Study.