Table 1.

Age-dependent AR, B-Raf, and P-ERK expressiona

No.GenotypeGenderWeeks
3824
AR
    1+/+M1.0 ± 0.1 (4)0.6 ± 0.0 (3)0.6 ± 0.0 (3)
    2Cy/+M1.1 ± 0.1 (4) NS2.4 ± 0.7 (3)b2.2 ± 0.2 (4)c
    3+/+F1.0 ± 0.1 (3)0.5 ± 0.1 (3)0.2 ± 0.0 (3)
    4Cy/+F0.9 ± 0.0 (3) NS0.5 ± 0.1 (3) NS0.2 ± 0.0 (3) NS
B-Raf
    5+/+M1.0 ± 0.0 (4)0.6 ± 0.1 (3)0.7 ± 0.1 (3)
    6Cy/+M1.4 ± 0.2 (4) NS1.2 ± 0.1 (3)c2.0 ± 0.2 (4)c
    7+/+F1.0 ± 0.0 (4)0.5 ± 0.1 (3)0.5 ± 0.1 (3)
    8Cy/+F1.0 ± 0.0 (3) NS0.8 ± 0.1 (3) NS0.8 ± 0.1 (3) NS
P-ERK
    9+/+M1.0 ± 0.0 (4)0.6 ± 0.1 (3)0.4 ± 0.0 (3)
    10Cy/+M1.0 ± 0.0 (4) NS1.0 ± 0.1 (3)c1.4 ± 0.1 (4)c
    11+/+F0.9 ± 0.1 (3)0.5 ± 0.1 (3)0.3 ± 0.1 (3)
    12Cy/+F1.0 ± 0.0 (3) NS0.6 ± 0.1 (3) NS0.6 ± 0.1 (3) NS
  • Data are means ± SE (n).

  • a Age 10 wk. +/+ versus Cy/+ in each gender-matched group. AR, androgen receptor; P-ERK, phospho–extracellular signal-regulated kinase 1/2.

  • b P < 0.05.

  • c P < 0.01.