Table 2.

P-selectin and ICAM-1 expression in mice with glomerulonephritisa

WT C57BL/6IL-12p40−/−IL-18−/−IL-12p40−/−/IL-18−/−
Glomerular P-selectin2.00 ± 0.191.77 ± 0.201.99 ± 0.152.11 ± 0.15
Glomerular ICAM-11.99 ± 0.181.36 ± 0.231.74 ± 0.181.50 ± 0.21
Interstitial ICAM-12.57 ± 0.122.06 ± 0.272.40 ± 0.092.15 ± 0.17
  • a Results are expressed as the mean ± SEM of the semiquantitative score of immunofluorescence intensity (0 to 3+). Numbers of mice studied are WT C57BL/6 (n = 7), IL-12p40−/− (n = 6), IL-18−/− (n = 5), and IL-12p40−/−IL-18−/− (n = 7). ICAM-1, intercellular adhesion molecule-1.