Table 4.

OR of developing CKD over 9 years of follow-up by quintile of HOMA-insulin resistancea

HOMA-Insulin Resistance QuintileUnadjusted RR (95% CI)Age-, Gender-, and Race-Adjusted RR (95% CI)Multivariable-Adjusted RR (95% CI)
Quintile 1 (<1.2)1.00 (Referent)1.00 (Referent)1.00 (Referent)
Quintile 2 (1.2 to 1.7)1.25 (0.95 to 1.64)1.19 (0.90 to 1.57)1.17 (0.88 to 1.54)
Quintile 3 (1.8 to 2.4)1.52 (1.17 to 1.97)1.48 (1.14 to 1.94)1.42 (1.08 to 1.87)
Quintile 4 (2.5 to 3.6)1.50 (1.15 to 1.95)1.44 (1.10 to 1.88)1.35 (1.02 to 1.80)
Quintile 5 (≥3.6)1.87 (1.45 to 2.41)1.91 (1.47 to 2.49)1.70 (1.26 to 2.30)
  • a Multivariable model adjusted for age, gender, race, education, BMI, ethanol and tobacco use, coronary heart disease, and physical activity. Model LR χ2 = 407.7, P < 0.001.