Table 5.

Factors associated with calcitriol: Bivariate and multivariate regression analyses using calcitriol as the dependent variable

Independent Variablesβ CoefficientSEtPy InterceptR2
Bivariate models
    FGF-23
        log FGF-23 (per log RU/ml)−26.607.06−3.77<0.00150.750.52
        (log FGF-23)24.921.283.84<0.001
        (log FGF-23)3−0.300.08−4.00<0.001
    covariates
        serum phosphate (per mg/dl)−0.510.14−3.610.0014.710.15
        log iPTH (per log pg/ml)−0.380.15−2.580.0124.590.08
        serum calcium (per mg/dl)0.590.212.770.007−2.640.09
        25-(OH)D3 (per ng/ml)0.030.012.630.0112.190.08
        eGFR (per ml/min per 1.73 m2)0.02<0.013.81<0.0012.230.16
Multivariate models
    FGF-23 and eGFR
        log FGF-23 (per log RU/ml)−25.127.15−3.510.00147.310.53
        (log FGF-23)24.691.293.640.001
        (log FGF-23)3−0.290.08−3.83<0.001
        eGFR (per ml/min per 1.73 m2)<0.010.001.190.237
    FGF-23 and serum phosphate
        log FGF-23 (per log RU/ml)−26.577.14−3.72<0.00150.720.52
        (log FGF-23)24.911.303.79<0.001
        (log FGF-23)3−0.300.08−3.95<0.001
        serum phosphate (per mg/dl)<0.010.13−0.040.971
    full multivariate model
        log FGF-23 (per log RU/ml)−20.367.44−2.730.00835.580.57
        (log FGF-23)23.841.352.850.006
        (log FGF-23)3−0.240.08−3.020.004
        serum phosphate (per mg/dl)−0.010.14−0.050.961
        log iPTH (per log pg/ml)0.170.161.090.280
        serum calcium (per mg/dl)0.160.190.850.396
        25-(OH)D3 (per ng/ml)0.020.012.060.043
        eGFR (per ml/min per 1.73 m2)0.010.011.860.067