Table 1.

Losartan- and PD123319-displaceable [3H]Ang II binding to PTEC after incubation with IgA-HMC–conditioned mediuma

Days after Incubation
02
PD12331953.29 ± 6.79b54.45 ± 7.24
Losartan43.72 ± 8.8043.62 ± 6.52
  • a Ang II, angiotensin II; PTEC, proximal tubular epithelial cells; HMC, human mesangial cells.

  • b Results were expressed as percentage of displaceable specific [3H]Ang II binding to PTEC compared with that of the binding in the absence of antagonists. Values represent mean ± SD from four experiments.