Table 1.

Mean calculated CrCl or GFR, mean absolute difference, bias, precision, and accuracy of GFR prediction equations compared to measured GFR

Mean CrCl/GFR (range)Mean Absolute DifferenceMedian Absolute DifferenceMedian % Absolute DifferenceBiasR2 (Precision)Pearson CorrelationAccuracy % within:
30%50%
CG129.6 ± 48.8(50.1–288.5)37.926.723%16.80.060.2458%79%
CORRECTED CG107.5 ± 28.9(57.8–259.2)24.521.519%−5.30.090.3078%97%
CG-GFR108.9 ± 41(42.1–242.3)32.930.525%−4.00.060.2559%83%
CORRECTED CG-GFR90.3 ± 24.2(48.6–217.7)28.527.524%−22.50.090.3061%96%
MDRD 197.6 ± 25(55.8–201.1)32.930.625%−15.20.030.1769%96%
MDRD 294.5 ± 25(50.3–184.9)28.723.522%−18.30.020.1565%95%
Jelliffe 192.3 ± 22.1(55.3–176.0)26.026.523%−13.20.050.2367%96%
CORRECTED JELLIFFE-186.5 ± 25.1(50.3–166.8)26.026.926%−26.30.030.1661%88%
  • Estimation equations:

    (1) Cockcroft-Gault (CG): CrCl × (1.73 m2/BSA): CrCl = ([(140 − age) × weight (kg)]/SCr × 72) × 0.85 (if female)

    (2) Cockcroft-Gault GFR (CG-GFR) estimate: GFR = 0.84 × CrCl by Equation (1)

    (3) MDRD 1: GFR = 170 × (SCr)−0.999 × (age)−0.176 × (0.762 if female) × (1.18 if black) × (BUN)−0.170 × (Alb)0.318

    (4) MDRD 2: GFR = 186 × (SCr)−1.154 × (age)−0.203 × (0.742 if female) × (1.212 if black)

    (5) Jellife 1: (1.73 m2/BSA): (98 − [0.8 × (age − 20)])/(SCr × [0.90 if female])