Table 1.

Demographic, BP, and echocardiographic data for ARVD and control groupsa

ARVDPbAOR (95% CI)c of ARVDPd
No (n = 50)Yes (n = 79)
Age (yr)69 ± 971 ± 7NS1.04 (0.98 to 1.10)0.2
Gender0.9
    male38.0%58.2%NS1
    female62.0%41.8%0.93 (0.37 to 2.32)
Diabetes30.0%24.1%NS0.81 (0.30 to 2.18)0.7
Ischemic heart disease22.0%32.9%NS1.56 (0.55 to 4.42)0.4
eGFR (ml/min)33 ± 1636 ± 19NS1.01 (0.98 to 1.03)0.8
24-h urinary protein (g/d)1.4 ± 2.00.4 ± 0.5<0.0010.21 (0.07 to 0.62)0.005
24-h systolic BP (mmHg)138 ± 17140 ± 19NS1.02 (1.00 to 1.05)0.07
24-h diastolic BP (mmHg)75 ± 1273 ± 13NS1.00 (0.96 to 1.04)0.9
Hemoglobin (g/L)124 ± 18127 ± 20NS0.99 (0.97 to 1.02)0.6
LV hypertrophy46.0%78.5%<0.0015.54 (2.04 to 15.02)0.001
LVMI (g/m2)116 ± 33183 ± 74<0.0011.04 (1.02 to 1.05)f<0.001
LVEF (%)57 ± 1253 ± 12NS0.97 (0.94 to 1.01)0.16
LVEDV index (ml/m2)34 ± 1682 ± 35<0.0011.18 (1.09 to 1.28)<0.001
Two or more LV diastolic function abnormalitiese12.0%40.5%<0.00116.3 (3.9 to 68.5)0.001
  • a AOR, adjusted odds ratio; ARVD, atherosclerotic renovascular disease; CI, confidence interval; eGFR, estimated GFR; LV, left ventricular; LVH, LV hypertrophy; LVMI, LV mass index; LVEF, LV ejection fraction; LVEDV, LV end-diastolic volume.

  • b Compared using the χ2 test for categorical variable and ANOVA test for continuous variables.

  • c Using multiple logistic regression, with the presence (coded 1) or absence (coded 0) of ARVD as the dependent variable and adjusted for age, gender, diabetes, ischemic heart disease, eGFR, 24-h urinary protein, 24-h systolic BP, and hemoglobin.

  • d Adjusted for age, gender, diabetes, ischemic heart disease, eGFR, 24-h urinary protein, and hemoglobin.

  • e Categories were combined because no patient in the control group had three diastolic function abnormalities.

  • f Each 1-g/m2 increment in LVMI is associated with a 4% increment in the AOR of ARVD.