Demographic, BP, and echocardiographic data for ARVD and control groupsa
ARVD | Pb | AOR (95% CI)c of ARVD | Pd | ||
---|---|---|---|---|---|
No (n = 50) | Yes (n = 79) | ||||
Age (yr) | 69 ± 9 | 71 ± 7 | NS | 1.04 (0.98 to 1.10) | 0.2 |
Gender | 0.9 | ||||
male | 38.0% | 58.2% | NS | 1 | |
female | 62.0% | 41.8% | 0.93 (0.37 to 2.32) | ||
Diabetes | 30.0% | 24.1% | NS | 0.81 (0.30 to 2.18) | 0.7 |
Ischemic heart disease | 22.0% | 32.9% | NS | 1.56 (0.55 to 4.42) | 0.4 |
eGFR (ml/min) | 33 ± 16 | 36 ± 19 | NS | 1.01 (0.98 to 1.03) | 0.8 |
24-h urinary protein (g/d) | 1.4 ± 2.0 | 0.4 ± 0.5 | <0.001 | 0.21 (0.07 to 0.62) | 0.005 |
24-h systolic BP (mmHg) | 138 ± 17 | 140 ± 19 | NS | 1.02 (1.00 to 1.05) | 0.07 |
24-h diastolic BP (mmHg) | 75 ± 12 | 73 ± 13 | NS | 1.00 (0.96 to 1.04) | 0.9 |
Hemoglobin (g/L) | 124 ± 18 | 127 ± 20 | NS | 0.99 (0.97 to 1.02) | 0.6 |
LV hypertrophy | 46.0% | 78.5% | <0.001 | 5.54 (2.04 to 15.02) | 0.001 |
LVMI (g/m2) | 116 ± 33 | 183 ± 74 | <0.001 | 1.04 (1.02 to 1.05)f | <0.001 |
LVEF (%) | 57 ± 12 | 53 ± 12 | NS | 0.97 (0.94 to 1.01) | 0.16 |
LVEDV index (ml/m2) | 34 ± 16 | 82 ± 35 | <0.001 | 1.18 (1.09 to 1.28) | <0.001 |
Two or more LV diastolic function abnormalitiese | 12.0% | 40.5% | <0.001 | 16.3 (3.9 to 68.5) | 0.001 |
↵a AOR, adjusted odds ratio; ARVD, atherosclerotic renovascular disease; CI, confidence interval; eGFR, estimated GFR; LV, left ventricular; LVH, LV hypertrophy; LVMI, LV mass index; LVEF, LV ejection fraction; LVEDV, LV end-diastolic volume.
↵b Compared using the χ2 test for categorical variable and ANOVA test for continuous variables.
↵c Using multiple logistic regression, with the presence (coded 1) or absence (coded 0) of ARVD as the dependent variable and adjusted for age, gender, diabetes, ischemic heart disease, eGFR, 24-h urinary protein, 24-h systolic BP, and hemoglobin.
↵d Adjusted for age, gender, diabetes, ischemic heart disease, eGFR, 24-h urinary protein, and hemoglobin.
↵e Categories were combined because no patient in the control group had three diastolic function abnormalities.
↵f Each 1-g/m2 increment in LVMI is associated with a 4% increment in the AOR of ARVD.