Table 2.

Univariate relationships between four baseline factors and risk for GFR event or ESRDa

Baseline FactorsHR (95% CI)P
Female gender1.05 (0.82 to 1.34)0.71
Age (per 10-yr increase)0.74 (0.67 to 0.83)<0.0001
UP/Cr (per doubling)1.59 (1.50 to 1.69)<0.0001
GFR (per 10-ml/min per 1.73 m2 decrease when GFR ≤40)1.71 (1.53 to 1.90)<0.0001
GFR (per 10-ml/min per 1.73 m2 decrease when GFR >40)1.07 (0.97 to 1.17)0.16
  • a Shown are the hazard ratios (HR) of the GFR event or ESRD composite outcome associated with female gender, with the designated increases in age, baseline proteinuria, and a reduced baseline GFR. Each baseline factor is considered individually, without controlling for the other factors. CI, confidence interval.