Table 5.

Mortality risk by Hb level

ParameterHb ≥ 11 g/dl (versus <11 g/dl; n = 379; HR [95% CI])Hb ≥10 and <11 g/dl (versus <10 g/dl; n = 137)Hb 11 to 12 g/dl (versus <10 g/dl; n = 195)Hb > 12 g/dl (versus <10 g/dl; n = 184)
Crude model (n = 677)0.37 (0.21 to 0.65)c0.58 (0.29 to 1.15)0.31 (0.14 to 0.65)c0.28 (0.13 to 0.61)c
Full modela (n = 641)0.38 (0.20 to 0.72)c0.46 (0.20 to 1.04)0.30 (0.19 to 0.74)c0.20 (0.07 to 0.56)c
Full model, excluding those without baseline Medicare or Medicaid (n = 340)0.30 (0.13 to 0.71)c0.17 (0.05 to 0.58)c0.15 (0.04 to 0.53)c0.11 (0.03 to 0.39)c
Full model, excluding patients who received a transplant (n = 461)0.38 (0.20 to 0.72)c0.47 (0.21 to 1.06)0.29 (0.12 to 0.74)c0.20 (0.07 to 0.56)c
Full model, excluding those with repeated measures (n = 466)0.35 (0.17 to 0.73)c0.54 (0.23 to 1.26)0.28 (0.10 to 0.81)c0.23 (0.08 to 0.66)c
Inflammatory modelb (n = 641)0.39 (0.21 to 0.75)c0.55 (0.27 to 1.14)0.34 (0.15 to 0.80)c0.24 (0.10 to 0.61)c
  • a Adjusted for age, race, gender, ESRD cause, dialysis vintage, vascular access type, Medicare/Medicaid insurance status, serum albumin level, serum ferritin level, baseline hypertension, baseline eGFR by Schwartz, iron use, and epoetin quartiles.

  • b Serum albumin level, serum ferritin level, iron use, and epoetin quartiles.

  • c P < 0.05.