Table 1.

Access characteristics and univariate analysis of clinical risk factors for FTMa

Clinical Characteristicsn (N = 422)% Total% FTMOR for FTM (95% CI)P
Age (mean [SD]; range)<0.01
    total: 58 (17.5; 17 to 90)422
    ≥65: 74 (5.8; 65 to 90)18443.618.52.23 (1.25 to 3.96)
    <65: 45.5 (12.4; 17 to 64)23856.49.2
Gender0.03
    male28667.810.80.54 (0.30 to 0.96)
    female13632.218.4
Race0.003g
    white27865.89.70.43 (0.24 to 0.75)
    black358.320.1
    other10925.920.2
Cause of ESRD
    hypertension10224.212.80.94 (0.48 to 1.83)0.86
    diabetes10424.616.41.40 (0.75 to 2.59)0.29
    glomerulonephritis11126.39.90.65 (0.32 to 1.31)0.22
    interstitial nephritis163.818.81.54 (0.42 to 5.57)0.51
    other/unknown8921.113.51.02 (0.52 to 2.03)0.95
Vintage on dialysis
    ≤6 mo33779.913.61.18 (0.57 to 2.45)0.65
    6 to 12 mo348.011.80.86 (0.29 to 2.55)0.79
    1 to 5 yr276.414.81.15 (0.38 to 3.46)0.80
    >5 yr245.78.30.58 (0.13 to 2.54)0.47
Comorbidities
    diabetesb12028.418.31.77 (0.98 to 3.17)0.05
    hypertension32176.014.61.75 (0.83 to 3.72)0.14
    CAD13632.222.12.83 (1.60 to 5.00)<0.01
    PVD358.328.62.97 (1.34 to 6.57)<0.01
    cerebrovascular diseasec389.010.50.75 (0.26 to 2.20)0.60
    congestive heart failured8716.018.41.66 (0.88 to 3.14)0.11
    dyslipidemiae8219.420.72.02 (1.08 to 3.79)0.03
    active smoker12429.412.90.96 (0.51 to 1.72)0.89
    overweightf5613.320.01.80 (0.89 to 3.66)0.10
Access placement
    previous catheter use21450.816.31.73 (0.97 to 3.09)0.06
    upper arm16338.611.00.73 (0.40 to 1.34)0.31
Surgeon (individual surgeon not shown)N/AN/A0.73
Anatomic configuration
    radiocephalic25660.7N/A
    brachiocephalic14534.4N/A
    transposed brachiobasilic184.2N/A
    femoral-saphenous30.7N/A
Side
    right11226.5N/A
    left31073.5N/A
  • a CAD, coronary artery disease; CI, confidence interval; FTM, failure to mature; OR, odds ratio; PVD, peripheral vascular disease.

  • b Defined when a patient had ever required hypoglycemic agents or insulin or when the diagnosis had been noted in the medical records at least twice by two different physicians; it includes those with diabetes as cause of ESRD.

  • c Defined as a stroke or transient ischemic attack documented by computed tomography scan, magnetic resonance imaging, or classical clinical signs and symptoms and confirmed by a neurologist or when the diagnosis had been noted in the medical records at least twice by two different physicians.

  • d Defined by classical signs and symptoms and either documentation by echocardiography or chest X-ray or complete symptom resolution with ultrafiltration.

  • e Hyperlipidemia conformed to our Canadian guideline definitions (24,25).

  • f Body mass index ≥30, consistent with the World Health Organization definition (26).

  • g White versus nonwhite.