Table 2.

Normal subjects and patients with diabetesa

ParameterNormalDiabetes
Baseline PRA (ng/AngI per ml/h)0.40 ± 0.10.63 ± 0.25
Peak PRA after captopril (ng AngI per ml/h)1.4 ± 0.3b3.0 ± 0.4
Prorenin (μU/ml)128.7 ± 5.8b175.7 ± 15.1
Active renin (μU/ml)14.5 ± 1.3b11.6 ± 0.9
Delta RPF (ml/min per 1.73 m2)13.6 ± 5.8c82.9 ± 11.5
Plasma aldosterone (ng/ml)2.3 ± 0.82.4 ± 0.8
  • a Data are means ± SEM. AngI, angiotensin I; PRA, plasma renin activity.

  • b P < 0.05.

  • c P < 0.01.