Table 1.

Treatment groups and characteristics of animalsa

WT Mice (n = 8 per Group)RAGE −/− Mice (n = 8 per Group)
Age (Weeks)Body Weight (g)Hematocrit (%)Age (Weeks)Body Weight (g)Hematocrit (%)
Sham1431.9 ± 1.70.53 ± 0.031432.8 ± 1.20.48 ± 0.03
Sham i.p.1430.8 ± 0.80.51 ± 0.021430.7 ± 1.20.53 ± 0.02
Filter-sterilized1431.5 ± 1.50.51 ± 0.041431.0 ± 1.20.51 ± 0.09
Glucose-free1431.9 ± 1.10.52 ± 0.021432.3 ± 2.00.52 ± 0.02
Low GDP1432.4 ± 1.00.52 ± 0.021430.2 ± 1.40.52 ± 0.05
High GDP1431.6 ± 1.30.51 ± 0.021433.3 ± 0.90.50 ± 0.04
  • a WT, wild-type; RAGE, receptor for advance glycation end-products; sham i.p., sham injection without instilling solution as a control for puncture trauma; GDP, glucose degradation products.