Table 1.

Definition of metabolic syndrome by WHO, NCEP ATP III, and IDFa

WHO Definition (2)NCEP ATP III Definition (3)IDF Definition (4)
Insulin resistance identified by type 2 diabetes or impaired fasting glucose or impaired glucose tolerance or insulin resistance (by insulin clamp) plus two or more of the following:
  • BMI >30 kg/m2 and/or waist:hip ratio >0.9 (male) and >0.85 (female)

  • Triglycerides ≥150 mg/dl

  • BP ≥140/90 mmHg and/or antihypertensive drugs

  • HDL cholesterol <35 (male) and <39 (female)

  • Microalbuminuria (albumin excretion rate ≥20 μg/min) or albumin:creatinine ratio ≥30 mg/g

Metabolic syndrome is defined by three or more of the following risk factors:
  • Waist circumference >88 cm (women) and >102 cm (men)

  • Triglycerides ≥150 mg/dl

  • HDL cholesterol <40 (male) and <50 (female)

  • BP ≥130/85 mmHg

  • Fasting glucose level ≥110 mg/dl

Central obesity (waist circumference, ethnicity specific) plus two or more of the following:
  • Triglycerides ≥150 mg/dl or treatment for this abnormality

  • HDL cholesterol <40 (male) and <50 (female) or specific treatment

  • BP ≥130/85 mg/dl or pharmacologic treatment

  • a IDF, International Diabetes Federation; NCEP ATP III, National Cholesterol Education Program Adult Treatment Panel III; WHO, World Health Organization.