Table 2.

Logistic regression models with development of hypertension after 4.2 yr of follow-up as dependent variablea

OR (95% CI)P Value
Model 1
    ln(UAE)1.43 (1.28 to 1.60)<0.001
Model 2
    ln(UAE)1.36 (1.22 to 1.53)<0.001
Model 3
    ln(UAE)1.17 (1.03 to 1.33)0.003
Model 4
    ln(UAE)1.18 (1.03 to 1.36)0.016
Model 5
    ln(UAE)2.69 (1.27 to 5.72)0.010
    eGFR1.30 (0.99 to 1.70)0.055
    ln(UAE) × eGFR0.90 (0.81 to 0.99)0.030
  • a OR for ln(UAE) is per 1-unit change; OR for eGFR is per 10 ml/min per 1.73 m2 change; model 1, crude model; model 2, adjusted for age and gender; model 3, model 2 + adjusted for baseline diastolic and systolic BP; model 4, model 3 + adjusted for baseline body mass index, smoking, alcohol use, sodium intake, levels of glucose, insulin, cholesterol, triglycerides, and high-sensitivity C-reactive protein; model 5, model 4 + inclusion of interaction term ln(UAE) × eGFR. OR, odds ratio; CI, confidence interval; ln(UAE), logarithmic transformed value of UAE; eGFR, estimated GFR.