Table 1.

Phenotype characterization of JRC-CRE micea

Observed ParametersScalingWT(n = 6)JRC-CRE(n = 6)
HairNormal (0) or unfit (1)00
PiloerectionNone (0) or marked (1)00
Body toneCompletely flaccid (0) to extreme resistance (2)11
Spontaneous activityNone (0), normal (1), or repeated vigorous movement (2)11
Provoked biting responseAbsent (0) or present (1)11
Tail elevatedFlattened (0), normal (1), or elevated (2)11
RespirationGasping, irregular (0), normal (1), or hyperventilation (2)11
Body weightWeight increase after 2 wk of doxycycline administration2.03 g2.06 g
  • a WT, wild type.