Table 2.

Risk for death by eGFR after stratification by age groupa

Age Group (Yr)eGFR 50 to 59(n = 266,421)eGFR 40 to 49(n = 142,257)eGFR 30 to 39(n = 67,659)eGFR 15 to 29(n = 33,213)GFR < 15(n = 5,300)
Unadjusted HR (95% CI)
    18 to 44 (n = 239,096)1.80 (1.50 to 2.16)2.85 (2.03 to 4.00)6.34 (4.52 to 8.88)9.01 (6.72 to 12.10)10.73 (7.18 to 16.03)
    45 to 54 (n = 501,258)1.39 (1.30 to 1.48)2.40 (2.21 to 2.60)4.24 (3.87 to 4.66)5.94 (5.41 to 6.52)6.37 (5.47 to 7.42)
    55 to 64 (n = 537,230)1.32 (1.27 to 1.38)2.26 (2.13 to 2.38)3.60 (3.38 to 3.84)5.09 (4.75 to 5.45)6.43 (5.71 to 7.24)
    65 to 74 (n = 686,702)1.14 (1.11 to 1.16)1.70 (1.65 to 1.74)2.63 (2.54 to 2.72)4.11 (3.95 to 4.27)5.75 (5.28 to 6.26)
    75 to 84 (n = 566,286)1.09 (1.07 to 1.11)1.41 (1.38 to 1.43)1.95 (1.91 to 2.00)2.99 (2.90 to 3.07)4.81 (4.50 to 5.16)
    85+ (n = 53,339)1.06 (1.02 to 1.11)1.20 (1.15 to 1.26)1.55 (1.15 to 1.26)2.20 (2.07 to 2.34)3.76 (3.18 to 4.45)
Adjustedb HR (95% CI)
    18 to 44 (n = 239,096)1.56 (1.30 to 1.88)1.90 (1.35 to 2.67)3.58 (2.54 to 5.05)4.92 (3.65 to 6.63)5.86 (3.91 to 8.80)
    45 to 54 (n = 501,258)1.27 (1.19 to 1.36)1.89 (1.74 to 2.06)2.89 (2.63 to 3.18)3.95 (3.59 to 4.35)4.47 (3.84 to 5.21)
    55 to 64 (n = 537,230)1.18 (1.13 to 1.23)1.75 (1.65 to 1.85)2.43 (2.27 to 2.59)3.19 (2.97 to 3.42)4.29 (3.81 to 4.84)
    65 to 74 (n = 686,702)1.02 (0.99 to 1.05)1.35 (1.32 to 1.39)1.81 (1.75 to 1.87)2.61 (2.51 to 2.72)3.82 (3.50 to 4.16)
    75 to 84 (n = 566,286)1.02 (0.99 to 1.04)1.21 (1.18 to 1.23)1.55 (1.51 to 1.58)2.21 (2.14 to 2.27)3.68 (3.44 to 3.95)
    85+ (n = 53,339)1.02 (0.97 to 1.06)1.10 (1.05 to 1.15)1.36 (1.29 to 1.44)1.86 (1.74 to 1.98)3.60 (3.05 to 4.26)
  • a CI, confidence interval; HR, hazard ratio; eGFR, estimated GFR (ml/min per 1.73 m2) based on the Modification of Diet in Renal Disease formula. Referent category is GFR ≥60 ml/min per 1.73 m2.

  • b Adjusted for age, race, gender, diabetes, congestive heart failure, coronary artery disease, peripheral arterial disease, stroke, chronic obstructive lung disease, and VA medical center.