Table 3.

Adjusted risk for death by age and eGFR among cohort members with stable repeat creatinine measurementsa

Age Group (Yr)Adjustedb HR (95% CI)
eGFR 50 to 59(n = 38,274)eGFR 40 to 49(n = 25,146)eGFR 30 to 39(n = 13,983)eGFR 15 to 29(n = 10,054)GFR < 15(n = 1,917)
18 to 44 (n = 42,477)1.24 (0.72 to 2.15)c2.77 (1.30 to 5.87)2.25 (1.16 to 4.37)4.21 (2.40 to 7.37)
45 to 54 (n = 132,344)0.86 (0.70 to 1.05)2.49 (1.21 to 1.84)1.90 (1.50 to 2.40)2.92 (2.46 to 3.47)3.26 (2.56 to 4.16)
55 to 64 (n = 148,669)0.96 (0.87 to 1.06)1.28 (1.12 to 1.48)1.77 (1.51 to 2.06)2.43 (2.15 to 2.76)3.27 (2.69 to 3.97)
65 to 74 (n = 167,874)0.90 (0.85 to 0.96)1.16 (1.09 to 1.24)1.55 (1.44 to 1.67)2.46 (2.29 to 2.64)2.73 (2.34 to 3.19)
75 to 84 (n = 125,313)0.94 (0.90 to 0.99)1.05 (1.00 to 1.10)1.43 (1.36 to 1.51)2.12 (2.00 to 2.23)3.06 (2.67 to 3.50)
85+ (n = 10,377)0.93 (0.83 to 1.04)1.04 (0.93 to 1.16)1.32 (1.17 to 1.49)1.83 (1.61 to 2.07)4.02 (2.94 to 5.51)
  • a Referent category is GFR ≥60 ml/min per 1.73 m2 (n = 537,680).

  • b Adjusted for age, race, gender, diabetes, congestive heart failure, coronary artery disease, peripheral arterial disease, stroke, chronic obstructive lung disease, and VA medical center.

  • c It was not possible to estimate the risk for mortality in this small group (n = 98) because there were no deaths during the follow-up period.