Table 3.

Serum data from Gcm2 null and wild-type mice at 12 wk of agea

Wild-Type (n = 4)Gcm2−/− (n = 4)P
FGF23 (pg/ml)94.8 ± 11.532.4 ± 3.30.0020
1,25(OH)2D3 (pg/ml)249.8 ± 50.758.2 ± 14.90.0223
Phosphate (mg/dl)7.7 ± 0.912.3 ± 0.60.0042
Calcium (mg/dl)8.2 ± 0.15.1 ± 0.40.0007
PTH (pg/ml)46.5 ± 8.815.6 ± 1.10.0131
  • a Data shown are serum marker from 12-wk-old mice. Data are expressed as mean ± SEM. The statistically significant difference was set at P < 0.05 by t test analysis. 1,25(OH)2D3, 1,25-dihydroxyvitamin D3.