Table 4.

Diagnostic performance characteristics of ICD-9-CM codes for ARF compared against two serum creatinine–based definitions at three Boston-area teaching hospitals in 2004

BWH(n = 41,800)MGH(n = 41,228)CSEMC(n = 14,677)Combined(n = 97,705)
Hou definitionb (%)
    sensitivity (%)26.229.330.228.3
    specificity (%)99.298.999.099.0
    PPV (%)79.981.177.980.2
    NPV (%)92.089.691.991.0
100% change
    sensitivity (%)32.235.147.635.4
    specificity (%)98.197.297.797.7
    PPV (%)47.448.447.547.9
    NPV (%)96.595.297.796.1
  • aNPV, negative predictive value; PPV, positive predictive value.

  • b Change of 0.5, 1.0, and 1.5 mg/dl for nadir serum creatinine ≤1.9, 2.0 to 4.9, and ≥5.0 mg/dl, respectively (6).