Table 2.

Clinical and hematologic parameters in patients with SS disease and other non-SS sickling hemoglobinopathies according to albuminuriaa

Age (yr; median)BMI (kg/m2)SBP (mmHg)DBP (mmHg)SCr (mg/dl)Hb (g/L)MCV (fl)CrCl (ml/min per 1.73 m2)Reticulocytes (%)LDH (U/L)
SS disease
    normo2922.6 ± 0.7121 ± 262 ± 10.7 ± 0.18.4 ± 0.293 ± 1132 ± 511 ± 1483 ± 26
    micro3220.9 ± 0.7b124 ± 263 ± 10.7 ± 0.18.2 ± 0.294 ± 2129 ± 614 ± 1550 ± 36
    macro3622.8 ± 0.9127 ± 2b,c69 ± 1b,c1.2 ± 0.2b,c8.1 ± 0.295 ± 2116 ± 713 ± 1471 ± 23
Other sickling diseases
    normo3329.4 ± 0.9127 ± 273 ± 20.8 ± 0.111.5 ± 0.283 ± 1127 ± 54 ± 1284 ± 13
    micro4127.2 ± 1.1131 ± 375 ± 20.9 ± 0.111.4 ± 0.386 ± 2112 ± 54 ± 1286 ± 18
    macro43b30.8 ± 1.2147 ± 6b,c86 ± 3b,c1.2 ± 0.2b,c11.1 ± 0.687 ± 2107 ± 155 ± 1330 ± 46
  • a DBP, diastolic BP; SBP, systolic BP; MCV, mean corpuscular volume.

  • b P < 0.05 versus normoalbuminuria.

  • c P < 0.05 versus microalbuminuria.\