Table 1.

Study and participant characteristicsa

CharacteristicOverallbStudyc
MDRD Study28cAASK6DCCT18DRDS40CSG41CRIC42CCF CKD5CCF Donors5Mayo CKD7Mayo Donors7
Study
    typeRSRSRSRSRSRSCPCPCPCP
    centerMCMCMCSCMCMCSCSCSCSC
    N550410851205787126266446695301221372
    dates1989 to 19921995 to 19981987 to 19891988 to 19931987 to 19922003 to 20051996 to 20031996 to 20031999 to 20001996 to 2002
Clinical
    age (mean [SD])47 (15)51 (13)54 (11)29 (6)42 (11)34 (8)55 (14)54 (16)42 (10)54 (14)41 (11)
        <40 (n [%])2029 (37)259 (13)136 (7)787 (39)51 (3)210 (1)78 (4)138 (7)149 (7)41 (2)180 (9)
        40 to 65 (n [%])2739 (50)663 (24)864 (32)0 (0)75 (3)56 (2)231 (8)368 (13)173 (6)126 (5)183 (7)
         >65 (n [%])736 (13)163 (22)205 (28)0 (0)0 (0)0 (0)137 (19)168 (23)0 (0)54 (7)9 (1)
    female (n [%])2397 (44)427 (39)414 (34)356 (45)75 (60)129 (48)214 (48)299 (43)191 (64)79 (36)214 (58)
    race (n [%])
        white and other3462 (63)875 (25)0764 (22)0235 (7)205 (6)563 (16)242 (7)217 (6)361 (10)
        black1737 (32)128 (7)1205 (69)10 (0.6)021 (1)194 (11)122 (7)50 (3)07 (0.4)
        Asian62 (1)11 (18)02 (3)01 (2)33 (53)6 (10)3 (5)3 (5)3 (5)
        Native American243 (4)71 (29)011 (5)126 (52)9 (4)14 (6)4 (2)6 (2)1 (0.4)1 (0.4)
    diabetes (n [%])1580 (29)68 (6)0787 (100)104 (83)266 (100)290 (43)148 (21)0 (0)16 (7)0
        typeType 2NoneType 1Type 2Type 1Type 1 and type 2Type 1 and type 2bType 1 and type 2
    transplant (n [%])251 (5)000000146 (21)0105 (48)0
    BMI (mean [SD])28 (6)27 (5)31 (7)24 (3)35 (4)25 (4)32 (8)28 (7)27 (4)29 (6)28 (5)
        <20 (n [%])189 (3)32 (17)28 (15)30 (16)018 (10)11 (6)40 (21)14 (7)4 (2)12 (6)
        20 to 25 (n [%])1671 (30)343 (21)200 (12)456 (27)12 (1)137 (8)72 (4)193 (12)95 (6)58 (3)105 (6)
        26 to 30 (n [%])1922 (35)421 (22)414 (22)269 (14)24 (1)88 (5)131 (7)221 (12)116 (6)83 (4)155 (8)
        <30 (n [%])1722 (31)289 (17)563 (33)32 (2)90 (5)23 (1)232 (13)241 (14)76 (4)76 (4)100 (6)
    GFR (mean [SD])68 (39)40 (21)57 (24)124 (20)115 (27)78 (33)51 (21)36 (30)106 (19)48 (25)100 (16)
    original Scr (mean [SD])1.79 (1.25)2.22 (1.13)1.90 (0.88)0.83 (0.14)0.81 (0.19)1.34 (0.45)1.81 (0.68)3.20 (2.05)0.83 (0.18)1.97 (0.97)1.04 (0.15)
    standardized Scr (mean [SD])1.65 (1.07)2.11 (1.07)1.72 (0.81)0.75 (0.13)0.67 (0.17)1.26 (0.41)1.72 (0.60)2.93 (1.82)0.83 (0.16)1.76 (0.96)0.84 (0.15)
  • a To convert Scr to SI units, multiply by 88.4. AASK, African American Study of Kidney Diseases and Hypertension; CCF, Cleveland Clinic Foundation; CRIC, Chronic Renal Insufficiency Cohort Study; CSG, Collaborative Study Group: Captopril in Diabetic Nephropathy Study; DCCT, Diabetes Control and Complications Trial; DRDS, Diabetic Renal Disease Study; MC, multicenter; RS, research study; SC, single center; Scr, serum creatinine.

  • b Column percentage.

  • c Row percentages.