Table 3.

Performance of the MDRD Study equation in subgroupsa

ParametereGFR <60 (mGFR 37 [18])eGFR ≥60 (mGFR 101 [28])
NDifference (Median [95% CI])% Difference (Median [95% CI])P30 (95% CI)NDifference (Median [95% CI])% Difference (Median [95% CI])P30 (95% CI)
Overall28740.9 (0.6 to 1.1)3.0 (2 to 3.7)82 (81 to 83)26308.3 (7.4 to 9.2)8.7 (7.5 to 9.7)84 (83 to 85)
Age (yr)
    <405850.7 (0.1 to 1.5)2.9 (0.2 to 4.9)84 (83 to 86)147310.6 (9.2 to 12.2)9.8 (8.6 to 10.8)83 (82 to 84)
    40 to 6517091.3 (1.0 to 1.8)4.1 (3.1 to 5.7)82 (81 to 83)10426.4 (5.2 to 7.8)7.5 (6.0 to 7.5)85 (84 to 86)
    >65580−0.4 (−0.8 to 0.4)−1.2 (−2.9 to 1.2)82 (80 to 84)115−0.3 (−5.3 to 2.3)−0.4 (−9.2 to 3.0)88 (85 to 91)
Gender
    female12121.0 (0.7 to 1.7)3.8 (2.4 to 5.5)81 (80 to 82)117911.3 (9.9 to 12.6)11.4 (9.9 to 12.8)82 (81 to 83)
    male16620.7 (0.4 to 1.1)2.4 (1.1 to 3.4)83 (82 to 84)14516.2 (5.2 to 7.5)6.6 (5.6 to 7.8)86 (85 to 87)
Race
    white and other16680.6 (0.3 to 0.9)2.3 (1 to 3.4)82 (81 to 83)179912.1 (10.9 to 12.9)11.7 (10.5 to 12.6)83 (82 to 84)
    black10851.2 (0.7 to 1.9)3.4 (1.9 to 5.1)82 (81 to 83)6430.1 (−1.4 to 1.5)0.2 (−2 to 2)88 (87 to 89)
    Asian444.2 (1.2 to 7.3)10.8 (3.7 to 20.9)89 (84 to 94)188.5 (−3.2 to 15.0.2)11.8 (−3.6 to 18)83 (74 to 92)
    Native American/Pacific Islander/Hispanic771.5 (−1 to 2.5)5.9 (−3.2 to 10.1)91 (88 to 94)1701.0 (−2.8 to 5.3)1.0 (−2.6 to 5.5)82 (79 to 85)
Diabetes
    yes5101.7 (0.8 to 2.4)5.1 (2.5 to 7.8)74 (72 to 76)107110.8 (8.7 to 12.5)9.6 (8 to 10.9)83 (82 to 84)
    no23640.7 (0.4 to 1.1)2.5 (1.4 to 3.5)84 (83 to 85)15596.8 (5.7 to 8.1)7.8 (6.5 to 9.5)85 (84 to 86)
Transplant
    yes1690.4 (−1.3 to 2.1)1.2 (−3.6 to 5.8)78 (75 to 81)72−7.6 (−11.7 to −2.9)−11.1 (−20.2 to −3.9)75 (70 to 80)
    no27050.9 (0.6 to 1.2)3.1 (1.9 to 3.9)83 (82 to 84)25588.7 (7.9 to 9.6)9.1 (8 to 9.9)84 (83 to 85)
BMI
    <2096−1.4 (−2.4 to 2)−4.7 (−10.9 to 8.3)74 (70 to 79)904.8 (−0.9 to 7.3)4.5 (−0.9 to 8.8)79 (75 to 83)
    20 to 25740−0.2 (−0.6 to 0.4)−0.6 (−2.4 to 1.7)80 (79 to 82)9279.6 (8.2 to 11)9.5 (7.5 to 10.6)83 (82 to 84)
    26 to 309991.3 (0.8 to 1.9)4.0 (2.6 to 5.5)85 (84 to 86)9389.0 (7.6 to 10.8)9.6 (8 to 11)87 (86 to 88)
    >3010391.3 (0.9 to 2)4.1 (2.7 to 5.8)82 (81 to 83)6756.6 (4.2 to 8.1)6.7 (5 to 9)83 (82 to 84)
  • a Units of GFR are in ml/min per 1.73 m2. Difference is calculated as mGFR − eGFR. Percent difference is calculated as (mGFR − eGFR)/mGFR.