Table 3.

Incidence and risk for ESRD by age and eGFR at baseline

Baseline eGFR (ml/min per 1.73 m2)Age GroupNo. of PatientsTime at Risk (yr)Treated ESRDIncidence of Treated ESRD, per 100 Person-Years (95% CI) aAdjusted Hazard Ratio (95% CI)b
≥6018 to 44239,265844,5741050.02 (0.01 to 0.02)1.00 (referent)
45 to 54462,1091,621,2154760.03 (0.02 to 0.03)1.58 (1.27 to 1.95)
55 to 64390,6761,363,6693770.03(0.02 to 0.03)1.25 (1.00 to 1.56)
65 to 74476,6431,636,2564800.03(0.02 to 0.04)0.95 (0.76 to 1.19)
75 to 84307,1371,010,0443060.03 (0.02 to 0.04)0.90 (0.71 to 1.14)
85 to 10021,92864,655110.01 (0.00 to 0.01)0.48 (0.26 to 0.90)
45 to 5918 to 4410293659100.29 (−0.03 to 0.61)1.00 (referent)
45 to 54630822,1011420.58 (0.42 to 0.73)1.63 (0.86 to 3.11)
55 to 6415,07552,8851600.32 (0.24 to 0.40)0.77 (0.40 to 1.46)
65 to 7450,368172,3173260.19 (0.15 to 0.23)0.43 (0.23 to 0.81)
75 to 8447,860156,3341720.11 (0.08 to 0.15)0.26 (0.14 to 0.50)
85 to 100497914,526130.09 (0.03 to 0.15)0.22 (0.09 to 0.49)
30 to 4418 to 443741208676.19 (3.98 to 8.39)1.00 (referent)
45 to 54237976993073.59 (2.94 to 4.23)0.59 (0.45 to 0.77)
55 to 64585419,1254182.15 (1.82 to 2.47)0.32 (0.25 to 0.42)
65 to 7417,89357,2887501.27 (1.12 to 1.43)0.19 (0.15 to 0.24)
75 to 8432,16499,0305760.61 (0.52 to 0.71)0.10 (0.08 to 0.13)
85 to 100405911,219250.23 (0.10 to 0.35)0.04 (0.03 to 0.07)
15 to 2918 to 4420047810620.29 (13.35 to 27.22)1.00 (referent)
45 to 541147277853117.19 (14.82 to 19.56)0.75 (0.61 to 0.93)
55 to 642106524784315.01 (13.40 to 16.61)0.60 (0.49 to 0.73)
65 to 74582814,93914639.31 (8.41 to 10.21)0.36 (0.30 to 0.45)
75 to 84796820,19312516.31 (5.65 to 6.96)0.26 (0.21 to 0.32)
85 to 10010402358632.65 (1.64 to 3.67)0.12 (0.09 to 0.17)
<1518 to 4497928367.49 (39.39 to 95.58)1.00 (referent)
45 to 5442141035580.83 (65.64 to 96.00)0.93 (0.73 to 1.19)
55 to 6452454043178.51 (66.93 to 90.09)0.81 (0.63 to 1.03)
65 to 74959118263451.10 (44.20 to 58.00)0.55 (0.43 to 0.70)
75 to 84857104546744.78 (38.26 to 51.30)0.47 (0.37 to 0.60)
85 to 1001331693429.23 (0.03 to 58.43)0.22 (0.15 to 0.34)
  • a Rates standardized to the gender-race mix of the entire study population.

  • b Adjusted for race, gender, diabetes, coronary artery disease, peripheral arterial disease, congestive heart failure, cerebrovascular disease, and Charlson score.