Table 2.

Comparisons of the RRR and ARR and the NNT for 5 yr to prevent one event, for stroke and cardiovascular events by baseline kidney functiona

ParameterIncidence Rate (per 100 person-years)RRR (95% CI)ARR over 5 yr (95% CI)NNT for 5 yr
Major vascular events
    CrCl <60 ml/min6.530 (14 to 42)8.8 (4.2 to 12.5)11
    CrCl ≥60 ml/min4.126 (14 to 37)5.3 (2.8 to 7.4)19
Stroke
    CrCl <60 ml/min4.235 (17 to 50)7.1 (3.5 to 9.9)14
    CrCl ≥60 ml/min2.827 (12 to 39)4.1 (1.8 to 6.0)25
  • a ARR, absolute risk reduction; NNT, number needed to treat; RRR, relative risk reduction