Table 1.

Genotype frequencies for nonsynonymous sites in patients with FSGS and control subjectsa

MutationAAEA
MAFGenotype, number (frequency)TotalMAFGenotype, number (frequency)Total
P20LC/CC/TT/TC/CC/TT/T
    FSGS0242 (1.00)002420.001128 (1.00)00128
    control0.008621 (1.00)8 (0.013)1 (0.002)6300.004279 (0.99)2 (0.007)0281
G42RG/GG/AA/AG/GG/AA/A
    FSGS0.017234 (0.97)8 (0.033)02420128 (1.00)00128
    control0.014616 (0.977)18 (0.03)06340280 (1.00)00280
R138QG/GG/AA/AG/GG/AA/A
    FSGS0.004245 (0.99)2 (0.01)02470.012127 (0.98)2 (0.02)0129
    control0.001636 (1.00)1 (0.002)06370.002280 (1.00)1 (0.004)0281
R229QG/GG/AA/AG/GG/AA/A
    FSGS0.01242 (1.00)5 (0.002)02470.047117 (0.91)12 (0.09)0129
    control0.013618 (0.975)16 (0.002)06340.039250 (0.92)21 (0.08)0271
A242VC/CC/TT/TC/CC/TT/T
    FSGS0.07209 (0.864)32 (0.13)1 (0.004)2420128 (1.00)00128
    control0.062531 (0.881)69 (0.11)3 (0.005)6030.002280 (1.00)1 (0.004)0281
  • a Minor allele frequency.