Table 1.

Characteristics at DCCT closeout by gender-specific quartile of waist circumferencea

CharacteristicQuartile of Waist Circumference
MenWomen
1st2nd3rd4th1st2nd3rd4th
Waist circumference (cm)77 ± 383 ± 189 ± 2100 ± 768 ± 374 ± 279 ± 290 ± 7
n170172170172147150148150
Age (yr)31 ± 735 ± 635 ± 637 ± 634 ± 734 ± 733 ± 734 ± 8
Duration of diabetes (yr)11 ± 412 ± 512 ± 512 ± 511 ± 512 ± 513 ± 512 ± 5
White race163 (96)165 (96)163 (96)171 (99)143 (97)147 (98)142 (96)141 (94)
Intensive therapy during DCCT76 (45)82 (48)77 (45)101 (59)68 (46)69 (46)74 (50)100 (67)
Active smoking37 (22)40 (23)37 (22)42 (24)37 (26)36 (24)38 (26)27 (17)
BMI (kg/m2)23 ± 225 ± 227 ± 229 ± 322 ± 224 ± 226 ± 230 ± 4
Systolic BP (mmHg)116 ± 11118 ± 10121 ± 11121 ± 11111 ± 12113 ± 11113 ± 12118 ± 11
Diastolic BP (mmHg)73 ± 875 ± 978 ± 879 ± 870 ± 973 ± 872 ± 976 ± 8
AER (mg/24 h)37 ± 14458 ± 37051 ± 16931 ± 11041 ± 30049 ± 26626 ± 6018 ± 35
LogAER2.5 ± 1.12.4 ± 1.22.6 ± 1.32.5 ± 1.02.2 ± 1.12.3 ± 1.22.5 ± 1.02.3 ± 1.0
AER ≥30 mg/24 h29 (17)17 (10)29 (17)20 (12)14 (9)21 (14)24 (16)20 (13)
HbA1c (%)8.4 ± 1.68.1 ± 1.68.4 ± 1.58.2 ± 1.48.3 ± 1.78.4 ± 1.78.3 ± 1.88.1 ± 1.4
Total cholesterol (mg/dl)170 ± 30175 ± 34180 ± 29193 ± 37177 ± 27181 ± 31184 ± 36191 ± 34
Triglycerides (mg/dl)79 ± 5079 ± 4190 ± 45110 ± 7068 ± 3877 ± 3782 ± 4190 ± 46
HDL (mg/dl)50 ± 1247 ± 1147 ± 1244 ± 1060 ± 1457 ± 1256 ± 1251 ± 11
LDL (mg/dl)104 ± 26112 ± 30115 ± 27127 ± 30103 ± 25109 ± 26112 ± 30121 ± 30
Creatinine clearance (ml/min)139 ± 26144 ± 35149 ± 30154 ± 33110 ± 25116 ± 24121 ± 27129 ± 28
Creatinine clearance (ml/min per 1.73 m2)128 ± 24126 ± 29127 ± 24124 ± 25117 ± 27116 ± 23117 ± 25117 ± 24
  • a Continuous variables are means ± SD; categorical variables are n (%). AER, albumin excretion rate; BMI, body mass index; DCCT, Diabetes Control and Complications Trial; HbA1c, glycosylated hemoglobin.