Table 2.

Baseline characteristics of patients with ARF by NADPH oxidase p22phox genotypesa

CharacteristicNADPH Oxidase p22phox GenotypesP
CC (n = 85)CT (n = 82)TT (n = 33)
Age (yr)64 (16)66 (13)66 (17)0.69
Male gender (%)5459450.45
Race (%)0.69
    white889488
    black649
    other623
Admission type (%)0.77
    medical737067
    surgical273033
Contributing cause of ARF (%)0.80
    ischemic262918
    nephrotoxic181518
    ischemic and nephrotoxic789
    septic61115
    multifactorial/other433740
Coexisting conditions (%)
    diabetes4446300.27
    heart failure1117150.49
    cirrhosis8960.98
    chronic lung disease2111150.20
    CKD2729300.93
ICU setting (%)6776790.30
APACHE II score15 (6)16 (6)17 (7)0.45
MOF score ≥2 (%)2529210.66
Sepsis (%)3851360.15
Serum creatinine (mg/dl)
    baseline value1.6 (0.6)1.6 (0.6)1.5 (0.7)0.56
    enrollment value3.8 (2.3)3.6 (2.0)3.6 (1.3)0.57
    peak value4.4 (2.5)4.8 (3.7)3.9 (1.4)0.80
    discharge value2.5 (1.5)2.7 (2.1)2.2 (1.3)0.56
Oliguria (%)2021180.95
  • a Data are means (SD) or percentages. APACHE II, Acute Physiology and Chronic Health Evaluation II; ARF, acute renal failure; CKD, chronic kidney disease; MOF, Multiple Organ Failure.