Table 3.

Baseline characteristics of patients with ARF by catalase genotypesa

CharacteristicCatalase GenotypesP
CC (n = 112)CT (n = 74)TT (n = 14)
Age (yr)66 (14)63 (17)66 (12)0.58
Male gender (%)5453640.77
Race (%)0.82
    white8892100
    black740
    other540
Admission type (%)0.60
    medical736671
    surgical273429
Contributing cause of ARF (%)0.24
    ischemic272622
    nephrotoxic181514
    ischemic and nephrotoxic7110
    septic5167
    multifactorial/other433257
Coexisting conditions (%)
    diabetes4045540.58
    heart failure179150.30
    cirrhosis11500.81
    chronic lung disease1516230.64
    chronic kidney disease2927310.88
ICU setting (%)7173770.97
APACHE II score16 (6)16 (7)15 (4)0.70
MOF score ≥2 (%)2231290.39
Sepsis (%)4243500.83
Serum creatinine (mg/dl)
    baseline value1.5 (0.6)1.6 (0.6)1.7 (0.8)0.90
    enrollment value3.7 (2.2)3.7 (1.9)3.5 (1.9)0.86
    peak value4.5 (3.4)4.5 (2.3)4.4 (2.2)0.74
    discharge value2.5 (1.7)2.6 (1.7)2.7 (1.8)0.84
Oliguria (%)1823210.69
  • a Data are means (SD) or percentages.