Table 6.

Association of NADPH oxidase p22phox and catalase genotypes with composite outcome of dialysis requirement or hospital deatha

Predictor VariableOR95% CIP
NADPH oxidase p22phox +242 T allele (versus CC genotype)
    unadjusted2.111.19 to 3.750.01
    adjusted for race, gender, and APACHE II score2.121.10 to 4.100.03
    adjusted for race, gender, age, and MOF score2.201.17 to 4.110.01
    adjusted for race, gender, age, and sepsis2.041.11 to 3.740.02
    adjusted for race, gender, age, APACHE II score, and CKD2.171.12 to 4.220.02
Catalase −262 T allele (versus CC genotype)
    unadjusted1.050.60 to 1.840.86
    adjusted for race, gender, and APACHE II score0.990.52 to 1.890.98
    adjusted for race, gender, age, and MOF score0.950.52 to 1.760.88
    adjusted for race, gender, age, and sepsis1.070.59 to 1.930.84
    adjusted for race, gender, age, APACHE II score, and CKD0.990.52 to 1.900.98
  • a CI confidence interval; OR, odds ratio.