Table 2.

Plasma aldosterone concentrations (pg/ml) in NKCC2A+/+ and −/− mice after 1 wk on control (0.3% NaCl), high-salt (4% NaCl), or low-salt diet (0.03% NaCl after a single dose of 40 mg/kg furosemide intraperitoneally)a

Aldosterone (pg/ml)Normal SaltHigh SaltLow Salt
NKCC2A+/+264 ± 5256 ± 21672 ± 108
NKCC2A−/−385 ± 3938 ± 15700 ± 58
  • a Data are means ± SEM; n = 10 for each group.