Table 5.

Adverse events of clinical interesta

ParameterControl(n = 66)Intravenous Iron(n = 66)
Adverse events (patients [events])35 (104)32 (69)
Related adverse events (n patients [n events])
    diarrhea, dyspepsia, dyspnea, dizziness, chest pain, back pain, and increased sweating0 (0)4 (7)
Serious adverse events (all unrelated; patient [events])9 (14)9 (12)
Cardiac adverse events (patients [events])
    cardiac arrest, CHF, cardiorespiratory arrest, endocarditis, MI, and arrhythmias4 (4)4 (4)
Blood disorders (patients [events])
    anemia and coagulation disorders4 (6)1 (1)
Vascular disorders (patients [events])
    arterial stenosis, gangrene, hematoma, hot flashes, hypertension, hypotension, and TIA13 (21)5 (5)
Infections (patients [events])
    bronchitis, cellulitis, conjunctivitis, fungal infections, furuncles, C. difficile, line infections, pneumonia, nasopharyngitis, sepsis, skin infections, URI, and UTI10 (13)8 (12)
  • a Short-term adverse events were similar in both groups. CHF, congestive heart failure; MI, myocardial infarction; TIA, transient ischemic attack; URI, upper respiratory infection; UTI, urinary tract infection.