Table 1.

CSS disease features in Cfh−/− and WT mice with renal transplantsa

Kidney → HostBUN (mg/dl)Albuminuria (μg/mg creatinine)GN Score (0 to 4)
WT → WT (n = 14)44.2 ± 2.045.1 ± 3.60.54 ± 0.29
WT → Cfh−/− (n = 8)73.6 ± 11.0b53.1 ± 6.91.81 ± 0.36b
Cfh−/− → WT (n = 12)54.4 ± 6.1c82.8 ± 7.0d0.83 ± 0.26
  • a BUN, blood urea nitrogen; CSS, chronic serum sickness; GN, glomerulonephritis; WT, wild-type.

  • b P < 0.05 versus the other two groups.

  • c P < 0.01 versus WT → WT.

  • d P < 0.001 versus the other two groups.