Table 1.

Differential diagnosis of nodular glomerulosclerosis

Diabetic glomerulosclerosis
Chronic membranoproliferative glomerulonephritis (primary or secondary)
    monoclonal Ig deposition disease
Organized glomerular deposition diseases
    fibrillary glomerulonephritis
    immunotactoid glomerulonephritis
    fibronectin glomerulopathy
    collagen III glomerulopathy
Chronic hypoxic or ischemic conditions
    Takayasu's arteritis with renal artery stenosis
    cyanotic congenital heart disease
    cystic fibrosis
Idiopathic nodular glomerulosclerosis (often associated with smoking and chronic hypertension)