Table 3.

Relationships between age at onset, familial incidence of HUS, serum creatinine at first flare, and C3 level and severity of outcome at 1 yra

Risk FactorsESRD or Death within the Year after Onset
HR (95% CI)P
Age at onset (per year)0.98 (0.97 to 1.00)0.16
Familial/sporadic HUS0.44
    familial HUS (n = 14)1
    sporadic HUS (n = 31)1.56 (0.50 to 4.85)
Serum creatinine at first flare (each 50 points)1.12 (1.01 to 1.24)0.03
C3 level0.99 (0.98 to 1.00)0.42
  • a CI, confidence interval; HR, hazard ratio.