Table 6.

Drug dosage and plasma concentration in the multitarget therapy group

ParameterBaseline Value (n = 20)Week 1 (n = 20)1 Mo (n = 20)3 Mo (n = 19)6 Mo (n = 18)9 Mo (n = 8)
MMF (g/d)0.91 ± 0.120.91 ± 0.120.93 ± 0.220.89 ± 0.200.88 ± 0.210.84 ± 0.18
MPA AUC0–12 h (mg·h/L)28.03 ± 7.1331.34 ± 6.4331.17 ± 7.5331.44 ± 9.4429.11 ± 7.80
Tacrolimus (mg/d)3.65 ± 0.483.65 ± 0.483.70 ± 0.863.57 ± 0.903.75 ± 1.033.75 ± 1.28
Ctrough (ng/ml)a5.90 ± 2.875.90 ± 1.515.86 ± 1.505.61 ± 1.296.19 ± 1.42
Prednisone (mg/d)35.7 ± 8.635.7 ± 8.635.7 ± 8.619.0 ± 6.710.2 ± 1.110.0 ± 0.0
  • a The blood trough concentrations (12 h postdose) of tacrolimus.