Table 4.

Degree of podocyte foot process effacement in 23 C1q nephropathy patients with NS and no lesions or FSGS by light microscopya

ParameterPodocyte Foot Process Effacement (n [%])P
Extensive (≥50%) (n = 12)Segmental (<50%) (n = 9)Absent (n = 2)
Mesangial ID11 (91.7)7 (77.8)1
Mesangial-capillary wall ID1 (8.3)2 (22.2)10.315
No therapy at renal biopsy8 (66.7)2 (22.2)0
Therapy at renal biopsyb4 (33.3)7 (77.8)20.055
  • a ID, immune deposits.

  • b Thirteen patients had been receiving corticosteroids for 23 d to 10 mo at the time of renal biopsy.