Table 1.

Changes in co-stimulatory molecule expression on CD11c+ DC within the kidney and within the renal draining LN before and after intrarenal antigen injection, expressed as a percentage of CD11c+ cells

ParameterKidneyRenal LN
0 h24 h0 hRenal LN 24 h
CD8019.0 ± 2.028.0 ± 7.017.0 ± 2.022.0 ± 1.0
CD8610.0 ± 0.229.0 ± 5.0a31.0 ± 4.065.0 ± 4.0a
Both CD80 and CD863.0 ± 0.316.0 ± 5.0a13.0 ± 2.016.0 ± 1.0
PD-L110.0 ± 1.029.0 ± 2.0a35.0b74.0 ± 3.0
PD-L220.0 ± 1.028.0 ± 3.039.0b52.0 ± 3.0
  • a P < 0.05.

  • b Pooled renal LN samples.