Table 1.

Glomerular TLR mRNA expression during murine MPGN

TLRWTTSLPTSLP/FcγRIIb−
30 D120 D30 D120 D
Relative to Cyclophilin (%)Relative to WT Mice at 30 DRelative to Cyclophilin (%)Relative to WT Mice at 30 DRelative to Cyclophilin (%)Relative to WT Mice at 30 DRelative to Cyclophilin (%)Relative to WT Mice at 30 DRelative to Cyclophilin (%)Relative to WT Mice at 30 D
TLR10.49 (±0.30)10.39 (±0.04)0.803.30 (±1.50)6.703.01 (±1.12)6.114.77 (±1.43)9.70
TLR20.54 (±0.04)10.58 (±0.04)1.073.13 (±1.28)5.802.07 (±0.51)3.834.44 (±1.24)8.23
TLR32.92 (±0.25)12.66 (±0.11)0.913.68 (±0.61)1.263.68 (±0.45)3.474.24 (±0.55)1.45
TLR41.25 (±0.19)10.94 (±0.28)0.753.82 (±0.71)3.071.36 (±0.46)1.098.50 (±1.52)6.83
TLR50.20 (±0.07)10.18 (±0.04)0.904.28 (±2.30)21.401.81 (±0.91)9.051.32 (±0.55)6.60
TLR60.22 (±0.12)10.19 (±0.02)0.863.73 (±1.67)16.951.67 (±0.67)7.592.07 (±0.79)9.40
TLR70.87 (±0.15)10.75 (±0.28)0.863.83 (±1.98)4.401.79 (±0.30)2.062.72 (±0.45)3.13
TLR80.03 (±0.001)10.10 (±0.02)3.332.27 (±1.44)75.670.81 (±0.25)27.000.67 (±0.22)22.33
TLR90.06 (±0.008)10.23 (±0.045)3.834.88 (±2.93)81.332.56 (±0.94)42.670.58 (±0.16)9.67
TLR110.07 (±0.008)10.28 (±0.04)4.002.43 (±0.04)34.712.32 (±0.80)33.140.40 (±0.09)5.71