Table 3.

Urinary concentrations of chemokines and cytokines according to study groupa

MarkersIndividuals with Normoalbuminuria, Reference Group (n = 74)Individuals with MicroalbuminuriaPb
Nondecliners(n = 43)Decliners(n = 28)
Measured concentrations (pg/ml)
    IL-60.7 (0.4, 1.4)0.5 (0.4, 1.2)1.2 (0.4, 12.0)0.0304
    IL-80.9 (0.2, 7.3)0.8 (0.1, 3.9)13.0 (2.7, 87.0)0.0001
    IP-104.9 (2.0, 48.0)4.6 (2.2, 37.0)47.0 (6.8, 217.0)0.0009
    MCP-139.0 (18.0, 70.0)51.0 (18.0, 78.0)76.0 (53.0, 168.0)0.0029
    MIP-1δ42.0 (12.0, 65.0)38.0 (13.0, 71.0)64.0 (47.0, 122.0)0.0014
Concentrations adjusted for urinary creatinine (pg/mg creatinine)
    IL-60.9 (0.3, 2.0)1.1 (0.4, 1.8)1.6 (0.6, 15.0)0.0780
    IL-81.0 (0.3, 4.9)0.8 (0.1, 3.9)15.0 (3.1, 79.0)0.0001
    IP-105.1 (3.1, 60.0)5.3 (2.6, 66.0)49.0 (6.9, 228.0)0.0021
    MCP-149.0 (25.0, 90.0)59.0 (32.0, 89.0)95.0 (55.0, 198.0)0.0054
    MIP-1δ50.0 (16.0, 97.0)48.0 (10.0, 91.0)80.0 (48.0, 155.0)0.0215
  • a Data are median (25th, 75th percentiles).

  • b Kruskal-Wallis test of the null hypothesis that all three groups are from the same distribution.