Table 1.

Characteristics of persons with and without moderate chronic kidney disease (CKD)

Moderate CKD (eGFRCG < 60 ml/min/1.73m2) (n = 286)No or Mild CKD (eGFRCG ≥ 60 ml/min/1.73m2) (n = 897)P
Age, yr (SD; range)69.6 (5.7; 58–94)59.6 (6.2; 54–84)<0.0001
Male, %115 (40.2)382 (42.6)0.48
Current smoker, %22 (7.7)106 (11.8)0.04
Hypertension, %196 (68.5)480 (53.5)<0.0001
Diabetes, %27 (9.4)91 (10.1)0.87
Systolic blood pressure, mmHg (SD)153.2 (20.9)146.1 (20.1)<0.0001
Diastolic blood pressure, mmHg (SD)83.3 (9.5)85.1 (9.1)0.005
Fibrinogen, mg/dl (SD)372 (89)348 (81)<0.0001
White cell count, ×109 (SD)6.4 (1.9)6.3 (1.6)0.27
Serum total cholesterol, mmol/L (SD)6.0 (1.1)6.0 (1.1)0.72
Serum triglycerides, mmol/L (SD)1.5 (0.8)1.6 (0.8)0.26
CFH Y402H polymorphism status
 YY36 (12.6)118 (13.2)
 YH133 (46.5)409 (45.6)
 HH117 (40.9)370 (41.3)0.87b
Creatinine, mg/dl (SD)1.17 (0.37)0.96 (0.14)<0.0001
eGFRCG, ml/min/1.73m2 (SD)a52.5 (9.9)82.7 (18.4)<0.0001
  • a Estimated using Cockcroft-Gault equation.

  • b P trend in category.