Table 2.

Results of segregation analysis of Gd-IgA1 in study cohort

ModelNo. of Parametersχ2dfP versus Free Model
Free9
Mendelian dominant41150.05
Mendelian recessive41350.02
Additive41350.02
Environmental61730.0008
Sporadic225,80870
Polygenic325,71360
Major recessive + polygenes5240.73
Major dominant + polygenes5040.99
Environmental + polygenes2170.99
  • —, not applicable. The significance of each model was estimated by computing the difference in natural log likelihoods between the general (free) model and the model of interest. This difference approximates a χ 2 statistic, with degrees of freedom (df) equal to the difference in the number of parameters used in the two models. The best fitting models are the ones that are not significantly different compared with the free model. A detailed table is included in supplemental materials online.