Table 1.

Vasopressin receptors, localization, and effectsa

V1aVascular smooth muscleVasoconstriction, myocardial hypertrophy
PlateletsPlatelet aggregation
MyometriumUterine contraction
V1b (V3)Anterior pituitaryACTH release
V2Basolateral membrane, collecting tubuleInsertion of AQP2 water channels into apical membrane
Induction of AQP2 synthesis
Vascular endotheliumvWF and factor 8 release
Vascular smooth muscleVasodilation
  • a AQP2, aquaporin 2; vWF, von Willebrand factor.