Table 2.

Median glomerulosclerosis index score for CRE(+);NOTCH-IC and CRE(−);NOTCH-ICa

ParameterMedian Glomerulosclerosis Index Score (Lower Quartile, Upper quartile) at Postnatal Age
P0P7P14P21P28P42
CRE(−);NOTCH-IC0 (0, 0)0 (0, 0)0 (0, 1)0 (0, 0)0 (0, 0)0 (0, 1)
(n = no. of glomeruli)(n = 163)(n = 361)(n = 232)(n = 232)(n = 108)(n = 216)
CRE(+);NOTCH-IC0 (0, 0)0 (0, 2)2 (1, 3)2 (1, 3)3 (1, 4)3 (2, 4)
(n = no. of glomeruli)(n = 186)(n = 307)(n = 183)(n = 205)(n = 182)(n = 209)
  • a n = 3 mice per age group.