Table 3.

Analysis of podocyte cell proliferation in glomeruli of CRE(+);NOTCH-IC and CRE(−);NOTCH-IC transgenic micea

Parameter% Ki67-Positive Podocytes at Postnatal Age
P7P21P28
CRE(−);NOTCH-IC0 ± 00 ± 00 ± 0
(n = no. of glomeruli)(n = 31)(n = 27)(n = 23)
CRE(+);NOTCH-IC12 ± 4b32 ± 6b38 ± 8b
(n = no. of glomeruli)(n = 22)(n = 12)(n = 16)
  • a n = 3 mice per age group.

  • b P < 0.001.