Table 4.

RR for selected cancer sites in relation to ACR quintiles and per 1-SD increase in log (ACR)a

ACR Quintile (mg/mmol)ColorectalLungBreastProstateRenalBladder
nRR (95% CI)anRR (95% CI)anRR (95% CI)anRR (95% CI)anRR (95% CI)anRR (95% CI)a
0.00 to 0.3417181512012121
0.34 to 0.47140.7 (0.3 to 1.5)91.0 (0.4 to 2.6)102.4 (0.8 to 7.6)251.2 (0.6 to 2.1)10.5 (0.0 to 5.4)31.6 (0.3 to 9.3)
0.47 to 0.66170.9 (0.5 to 1.9)202.5 (1.1 to 5.6)92.1 (0.6 to 6.8)211.0 (0.5 to 1.9)31.5 (0.2 to 8.9)41.7 (0.3 to 10.0)
0.66 to 1.11140.7 (0.3 to 1.4)141.6 (0.7 to 3.9)112.5 (0.8 to 8.0)211.0 (0.5 to 1.8)42.0 (0.4 to 11.0)73.0 (0.6 to 15.0)
1.11 to 24.82281.3 (0.7 to 2.5)262.4 (1.1 to 5.5)102.4 (0.8 to 7.9)231.0 (0.5 to 1.8)72.8 (0.6 to 14.0)198.3 (1.9 to 36.0)
P trend0.320.0140.200.760.066<0.001
Per 1-SD increase in log (ACR)901.14 (0.95 to 1.38)771.21 (1.00 to 1.45)451.12 (0.84 to 1.49)1101.04 (0.87 to 1.25)171.44 (1.00 to 2.07)351.82 (1.45 to 2.28)
  • a Adjusted for age, gender, BMI, inactivity, and smoking habits (never smokers, ex-smokers/<10 cigarettes/d, ex-smokers/≥10 cigarettes/d, current smokers/<10 cigarettes/d, current smokers/10 to 19 cigarettes/d, current smokers/≥20 cigarettes/d). Breast cancer includes only women and is not adjusted for gender.