Table 4.

Adjusted incidence rate ratio (95% confidence interval) of all-cause and cardiovascular mortality, by category of eGFR: NHANES IIIa

ParametereGFR Based on Creatinine, Age, Race, and Gender (ml/min per 1.73 m2)
≥12090 to 11960 to 8930 to 5915 to 29Overall
All-cause mortality: eGFR based on cystatin C, age, race, and gender (ml/min per 1.73 m2)
    ≥1200.48 (0.15 to 1.54)1.38 (0.76 to 2.50)0.36 (0.05 to 2.62)bb0.93 (0.56 to 1.56)
    90 to 1191.32 (0.83 to 2.11)1.00 (Ref)0.76 (0.51 to 1.13)bb1.00 (Ref)
    60 to 891.89 (1.19 to 3.00)1.05 (0.78 to 1.41)0.94 (0.72 to 1.22)1.01 (0.68 to 1.50)b1.03 (0.84 to 1.26)
    30 to 59b1.73 (1.14 to 2.61)1.46 (1.10 to 1.94)1.76 (1.32 to 2.35)b1.68 (1.35 to 2.09)
    <30bb2.38 (1.01 to 53.61)3.33 (2.30 to 4.81)2.90 (1.81 to 4.63)3.25 (2.42 to 4.37)
    Overall1.36 (1.02 to 1.83)1.00 (Ref)0.94 (0.81 to 1.09)1.42 (1.20 to 1.68)2.39 (1.64 to 3.48)
Cardiovascular mortality: eGFR based on cystatin C, age, race, and gender (ml/min per 1.73 m2)
    ≥120c1.61 (0.55 to 4.70)cbb0.97 (0.34 to 2.73)
    90 to 1190.60 (0.18 to 2.02)1.00 (Ref)0.75 (0.37 to 1.52)bb1.00 (Ref)
    60 to 891.87 (0.82 to 4.26)1.17 (0.70 to 1.97)1.12 (0.70 to 1.79)0.92 (0.46 to 1.84)b1.29 (0.90 to 1.86)
    30 to 59b2.13 (1.09 to 4.14)1.83 (1.12 to 3.00)2.40 (1.47 to 3.93)b2.39 (1.63 to 3.50)
    <30bbb3.61 (1.96 to 6.63)3.74 (1.82 to 7.67)4.15 (2.56 to 6.71)
    Overall0.84 (0.45 to 1.57)1.00 (Ref)1.03 (0.82 to 1.30)1.61 (1.25 to 2.08)2.50 (1.44 to 4.34)
  • aAdjusted for age, gender, race/ethnicity, previous CVD, BP category, use of antihypertensive medication, diabetes status, smoking status, body mass index, LDL and HDL cholesterol, log triglycerides, and CRP category.

  • bn < 30.

  • cNo deaths.